Tocopherol Nicotinate, Vitamin E Nicotinate(CAS 43119-47-1)
Product Name: Tocopherol Nicotinate
INCI Name: Tocopherol Nicotinate
CAS No.: 43119-47-1
Grade: Cosmetic Premium Grade (Microcirculation Activating & Brightening Special)
Purity: ≥99.0%
Appearance: Light Yellow Transparent Viscous Oil, Pure Texture, No Impurities, No Peculiar Smell, Good Fluidity
Molecular Formula: C₃₄H₅₃NO₃
Molecular Weight: 527.79
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent lipophilic solubility, compatible with all oil-phase formulas; good formula stability, not easy to oxidize and deteriorate; excellent compatibility with VE, VC derivatives, plant oils and lipophilic active ingredients, easy for formula deployment and industrial mass production
Core Efficacy: Dual-effect integration of Vitamin E and Niacinamide; activate skin microcirculation, improve facial dullness, sallow and sluggish complexion; powerful lipophilic antioxidant capacity, scavenge oil-phase free radicals, inhibit lipid peroxidation; repair skin barrier, relieve dryness and roughness; anti-aging and fine line improvement, uniform skin tone
Key Characteristics: High-efficiency compound modified Vitamin E derivative, organically combines the antioxidant property of tocopherol and the brightening and microcirculation-improving advantages of niacin; stable molecular structure, no irritation and no flushing reaction; better skin permeability and efficacy sustainability than ordinary VE; solve the dull skin problem from root by improving blood circulation, with dual brightening and anti-aging effects
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent oxidation and efficacy attenuation
Shelf Life: 24 Months
Application: Widely used in brightening face oil, antioxidant lotion and cream, anti-aging skincare products, barrier repair formulas, dullness improvement and daily moisturizing functional cosmetics
Tocopherol Nicotinate, Vitamin E Nicotinate, VE Derivative, Microcirculation Brightening, Antioxidant, Anti-aging, Improve Dull Skin, Repair Barrier, Skincare Raw Material
Tocopherol Nicotinate, Vitamin E Nicotinate(CAS 43119-47-1)
Cosmetic Grade Tocopherol Nicotinate (TPN) is a high-performance compound lipophilic skincare active ingredient, a upgraded derivative of traditional Vitamin E. Through molecular esterification modification, it organically combines α-tocopherol (Vitamin E) and nicotinic acid (Vitamin B3), retaining the core advantages of two classic skincare ingredients and making up for the single efficacy of ordinary VE and common niacin ingredients.
Different from conventional antioxidant ingredients that only scavenge free radicals, TPN has dual core mechanisms of microcirculation activation + lipophilic antioxidant. It can effectively accelerate superficial skin blood microcirculation, improve the problem of slow skin metabolism and sluggish oxygen and blood supply, fundamentally fade long-term dullness, sallow and dark complexion caused by poor circulation.
Meanwhile, as an excellent lipophilic antioxidant, it can penetrate the lipid layer of the skin, efficiently scavenge oil-phase free radicals, inhibit lipid peroxidation and cell oxidative damage, delay skin light aging and dry aging. In addition, TPN can nourish and repair the skin barrier, enhance skin moisture-locking capacity, relieve dryness, roughness and fine dry lines, and improve overall skin texture. With stable molecular activity, no irritation, no photosensitivity and no flushing reaction, it is a safe and efficient multi-functional anti-aging and brightening raw material, perfectly compatible with oil-phase skincare systems.
Key Benefits
• Dual Nutrient Synergy, Double Efficacy: Integrates Vitamin E antioxidant and Vitamin B3 microcirculation brightening effects, achieves one-stop improvement of dullness, oxidation aging and rough skin, more comprehensive than single VE or niacin ingredients.
• Root Brightening by Activating Microcirculation: Accelerate skin blood and oxygen circulation, improve sluggish metabolism, fade sallow and dull complexion caused by poor circulation, solve "stuffy dark skin" that ordinary antioxidants cannot improve.
• Powerful Lipophilic Antioxidant, Anti-aging: Excellent oil-soluble oxidation resistance, target scavenge skin lipid free radicals, inhibit lipid peroxidation, delay dry aging and light aging, maintain skin youthful state.
• Barrier Nourishment & Moisturizing Repair: Nourish skin lipid barrier, enhance skin water-locking ability, relieve dryness, tightness and rough texture, improve dry fine lines and make skin smooth and delicate.
• Stable & Mild, No Side Effects: Optimized esterified molecular structure, stable activity without decomposition; no skin irritation, no photosensitive risk, no flushing and redness problems of high-concentration niacin, suitable for long-term use.
• Perfect Oil-phase Compatibility, Easy Mass Production: Pure lipophilic ingredient, highly compatible with all oil-based formulas, stable compounding with various oils and lipophilic actives, simple formula debugging and high finished product qualification rate.
Applications
• Brightening Facial Oil & Essence Oil: Core active ingredient of brightening oil-based skincare products, activate microcirculation to fade sallowness, resist oil-phase oxidation, and create translucent and bright skin tone.
• Anti-aging Moisturizing Lotion & Cream: Added in medium and high-end anti-aging cream formulas, scavenge lipophilic free radicals, delay skin aging, improve dry fine lines and rough texture, firm and moisturize skin.
• Barrier Repair & Soothing Skincare: Applied in barrier repair formulas, nourish lipid barrier, relieve dry and sensitive skin discomfort, enhance skin resistance, and stabilize skin health state.
• Daily Antioxidant Maintenance Products: Used in daily antioxidant and brightening skincare, prevent skin dullness and yellowing caused by oxidation and poor circulation, maintain long-term bright skin state.
• Night Repair & intensive Nourishing Series: Suitable for night intensive nourishing and repair formulas, continuously activate skin metabolism, repair daily oxidative damage, and brighten tired dull skin.
• Compound Brightening & Anti-aging System: Perfectly compounded with VC derivatives (EAA/MAP/SAP), nicotinamide and plant squalane to build water-oil dual anti-oxidation and multi-dimensional brightening system, greatly improve comprehensive skincare efficacy.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Tocopherol Nicotinate (TPN) | Compliant |
CAS No. | 43119-47-1 | Compliant |
Appearance | Light Yellow Transparent Viscous Oil | Compliant |
Purity (HPLC) | ≥99.0% | 99.58% |
Refractive Index | 1.480~1.500 | 1.491 |
Loss on Drying | ≤0.2% | 0.08% |
Acid Value | ≤1.0 mgKOH/g | 0.32 mgKOH/g |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Tocopherol Nicotinate?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 0.5%-2% for daily moisturizing and antioxidant products; 2%-5% for high-efficiency brightening and anti-aging oil-based formulas, adjustable according to product efficacy positioning.
• Q4: What is the difference between TPN and ordinary Vitamin E?
A4: Ordinary VE only has single antioxidant and moisturizing effect; TPN is a compound derivative of VE and niacin, with unique microcirculation activating and dullness-improving effects, solving sallow and dull skin from the root, with more comprehensive efficacy and better skin brightening performance.
• Q5: Is TPN suitable for sensitive skin formulas?
A5: Yes. TPN adopts stable esterified structure, no free niacin irritation, no flushing and redness reaction, mild and non-irritating, safe for sensitive skin long-term moisturizing and brightening care.
• Q6: What ingredients is it suitable for compounding?
A6: It can be perfectly compounded with VC derivatives (EAA/MAP/SAP), nicotinamide, squalane and plant essential oils to build water-oil dual anti-oxidation and multi-dimensional brightening system, optimizing skin brightening and anti-aging effects.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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